Continuous-time digital twin with analog memristive neural ordinary differential equation solver

Science Advances, 2025

Hegan Chen†, Jichang Yang†, Jia Chen†, Songqi Wang, Shaocong Wang, Dingchen Wang, Xinyu Tian, Yifei Yu, Xi Chen, Yinan Lin, Qifan Zhu, Yangu He, Xiaoshan Wu, Yi Li, Xinyuan Zhang, Ning Lin, Meng Xu, Yi Li, Xumeng Zhang, Xiaojuan Qi, Zhongrui Wang, Han Wang, Dashan Shang, Qi Liu, Kwang-Ting Cheng, Ming Liu

Digital twins, which replicate real-world entities through computational models, are transforming manufacturing and automation. While recent advances in machine learning have enabled data-driven digital twin development using discrete-time data and finite-depth models on digital hardware, these approaches face significant limitations. They struggle to capture continuous-time dynamics and model complex systems, and suffer from substantial time and energy overheads due to physically separated storage and processing as well as frequent analog-digital (A/D) conversions. Here, we propose a memristive neural ordinary differential equation (ODE) solver for digital twins. Our approach is intrinsically time-continuous using infinite-depth neural networks to model complex dynamics. Fully analog memristor arrays collocate storage and computation, addressing the von Neumann bottleneck and reducing A/D conversion requirements. We experimentally validate our solver on digital twins of HP variable-resistor model and Lorenz96 dynamics, demonstrating a 166.5-fold/369.3-fold speedup and a 499.0-fold/673.9-fold improvement in energy efficiency, respectively. This work paves the way to future digital twins for Industry 4.0.

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